Thanks. I pretty much decided to run it in front, for one thing, I am really liking the effects using stereo with two amps. My concern now is what caused that Amplifier tube to "red plate". That could have been due to some other factor, and was just coincidental. However that Amp never malfunctioned again after removing the Pitchfactor from the effects loop, and as I mentioned when I tried it with another Carvin amplifier, I heard crackles (which occurs before a tube starts to red plate). But I can't say definitively if the Pitchfactor was the casual factor. At some point, certainly while still in warranty, I will test this again and see if the phenomena repeats. If so I will get back to you.