I deduce that you are using a Timefactor.
When you select an effect with the encoder knob, it loads certain default parameters to give it the desired sound.
Because the knobs are not motorized (people already find these boxes expensive) the knob position does not correspond to the current setting. If the knob is moved, it will update the parameter.
The previous effect settings are stored in PitchFactor (until powerdown), and will be in a future version of TimeFactor. Until then Italo is right – you have to save things you want to keep.