Can you be more specific with the issue you are having?
If you set Program Kill Dry > On, then the dry signal will be removed from the Program mix. Bypassing the Program or turning the Mix level to 0 will result in no audio.
If Global Kill Dry > On, and Program Kill Dry > Global, you should get the same results as above.
Please provide some more information if this is not what you are experiencing, or if you are expecting something different.
